Alveolar Type II Cells Escape Stress Failure Caused by Tonic Stretch through Transient Focal Adhesion Disassembly

Mechanical ventilation-induced excessive stretch of alveoli is reported to induce cellular stress failure and subsequent lung injury, and is therefore an injurious factor to the lung.Avoiding cellular stress failure is crucial to ventilator-induced lung injury (VILI) treatment.In the present study, primary rat alveolar type II (ATII) cells were iso

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A dynamic mode of mitotic bookmarking by transcription factors

During mitosis, transcription is shut off, chromatin condenses, and most transcription factors (TFs) are reported to be excluded from chromosomes.How do daughter cells re-establish the original transcription program? Recent discoveries that a select set of TFs remain bound on mitotic chromosomes suggest a potential mechanism for maintaining transcr

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Change in phenotypic plasticity of a morphological defence in Daphnia galeata (Crustacea: Cladocera) in a selection experiment

Some water fleas Daphnia change their head morphology to reduce predation risk in response to chemical substances (kairomones) released from larvae STYLING MOUSSE of the invertebrate predator Chaoborus (Insecta: Diptera).We tested for evidence of the costs associated with elongation of the head spine in Daphnia galeata and the consequences of these

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